Microvascular function is impaired in children with morbid obesity
نویسندگان
چکیده
منابع مشابه
Impaired microvascular function in obesity: implications for obesity-associated microangiopathy, hypertension, and insulin resistance.
BACKGROUND Obesity is associated with an increased risk of developing microangiopathy, hypertension, and insulin resistance. We hypothesized that obesity is a primary cause of microvascular dysfunction, which may contribute to the development of these obesity-related disorders. METHODS AND RESULTS We examined microvascular function in 16 lean (body mass index <24 kg/m2) and 12 obese (body mas...
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BACKGROUND Intracranial lesions may affect the hypothalamo-hypophyseal axis and lead to some neuro-endocrinological dysfunctions (hyperphagia, sleep disorders and hormonal dysfunctions). There is a very limited number of studies about childhood obesity and intracranial lesions. AIMS To evaluate the incidence of intracranial lesions and its role in clinical symptoms and aetiology in cases with...
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INTRODUCTION AND OBJECTIVES The effect of obesity on cardiac function is still under discussion. The objective of this study was to assess cardiopulmonary capacity in morbidly obese patients. Patients and method. A symptom-limited cardiopulmonary exercise stress test was carried out in 31 morbidly obese patients (BMI 50 9 kg/m2) and 30 normal controls (BMI 24 2 kg/m2. Cardiovascular function wa...
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Introduction: Roux-en-Y gastric bypass (RYGB) reduces weight and long-term cardiovascular risk in obese patients. We showed that endothelial-mediated vasorelaxation improves rapidly in diet-induced obese (DIO) rats within 8 days after RYGB and is associated with reduced activation of JNK independently from weight loss. Purpose: We investigated whether in vivo inhibition of JNK with two differen...
متن کاملImpaired skin microvascular function in children, adolescents, and young adults with type 1 diabetes.
OBJECTIVE Vascular disease in type 1 diabetes is a complex and multifactorial process, which probably begins in childhood in association with the onset of diabetes. To determine the possible factors involved, we measured microvascular responses to endothelium-dependent (acetylcholine) and endothelium-independent (sodium nitroprusside) vasodilators in 56 patients with type 1 diabetes (aged 9-22 ...
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ژورنال
عنوان ژورنال: Vascular Medicine
سال: 2011
ISSN: 1358-863X,1477-0377
DOI: 10.1177/1358863x11400780